Adjuvant Phytotherapy against Antitubercular Drug Induced Hepatotoxicity
نویسندگان
چکیده
منابع مشابه
Adjuvant Phytotherapy against Antitubercular Drug Induced Hepatotoxicity
Tuberculosis was declared as a global pandemic and panic because the causative Mycobacterium tuberculosis can kill an incredible number of individuals which formulate a major obstacle to social and economic development of the country. Most of the developing countries are affected by tuberculosis. Antitubercular therapy involves the use of Directly Observed Therapy Short (DOTS) course for 6-9 mo...
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In the present study, the hepatoprotective activity of hydroalcoholic extract of Selaginella corymbosa leaves was investigated. Qualitative test confirmed the presence of flavonoids, sterols and saponins in the extract. The extract was studied for isoniazid and chloroquine induced hepatic injury using 500mg/kg oral dose in albino rats. The changes were assessed by serum enzyme profile, which in...
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N Engl J Med 2003;349:474-85. Copyright © 2003 Massachusetts Medical Society. n the past five years, two drugs have been withdrawn from the market by the Food and Drug Administration (FDA) for causing severe liver injury, a potential danger that had not been fully recognized in the course of the preapproval clinical trials. Reports of adverse drug reactions of any type engender fear and skeptic...
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Background: Arsenic trioxide (As2O3) has shown effectiveness in the treatment of leukemia, but it is also associated with hepatotoxicity. Given antileukemic drug-induced oxidative stress and toxicity, this study focused on the mitigatory role of eugenol, a monoterpene compound from clove oil, in the hepatic tissue of Wistar rats.Methods: Twenty-four male Wistar rats (180–250 g) were randomly di...
متن کاملDrug and Alcohol Induced Hepatotoxicity
Drug induced hepatotoxicity is the most common reason cited for withdrawal of already approved drugs from the market and accounts for more than 50 percent of cases of acute liver failure in the United States. Ethanol (EtOH) causes a further substantial amount of liver insufficiencies world wide. The current thesis was focused on the mechanisms behind hepatotoxicity caused by these agents. Using...
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ژورنال
عنوان ژورنال: Journal of Bioanalysis & Biomedicine
سال: 2016
ISSN: 1948-593X
DOI: 10.4172/1948-593x.1000e147